Invention Grant
- Patent Title: DACOS type NNRTIS amino acid ester derivative, preparation method thereof, pharmaceutical composition, and application thereof
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Application No.: US16977867Application Date: 2019-03-04
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Publication No.: US11420959B2Publication Date: 2022-08-23
- Inventor: Yanping He , Hongbin Zhang , Yongtang Zheng , Yufang Zhang , Chengrun Tang , Wei Ding , Liumeng Yang , Yiming Li
- Applicant: YUNNAN UNIVERSITY , KUNMING INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES
- Applicant Address: CN Kunming; CN Kunming
- Assignee: YUNNAN UNIVERSITY,KUNMING INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES
- Current Assignee: YUNNAN UNIVERSITY,KUNMING INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES
- Current Assignee Address: CN Kunming; CN Kunming
- Agency: Pilloff Passino & Cosenza LLP
- Agent Sean A. Passino; Rachel K. Pilloff
- Priority: CN201810183281.7 20180306
- International Application: PCT/CN2019/076842 WO 20190304
- International Announcement: WO2019/170051 WO 20190912
- Main IPC: C07D239/56
- IPC: C07D239/56 ; C07D403/12 ; A61P31/18
Abstract:
Disclosed is a DACOs-type NNRTIs amino acid ester derivative, a preparation method thereof, a pharmaceutical composition, and an application thereof. The structure of the DACOs-type NNRTIs amino acid ester derivative is represented by formula (I). The DACOs-type NNRTIs amino acid ester derivative represented by formula (I) can be used as HIV-1 inhibitors and for the preparation of a drug for treating and/or preventing immunodeficiency viruses.
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