Invention Grant
- Patent Title: Modified HSV gB protein and HSV vaccine including same
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Application No.: US16641432Application Date: 2018-08-29
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Publication No.: US11421002B2Publication Date: 2022-08-23
- Inventor: Hiroaki Mori , Tomohiro Nishimura , Hiroyuki Shimizu , Miyuki Matsumoto
- Applicant: KM Biologics Co., Ltd.
- Applicant Address: JP Kumamoto
- Assignee: KM Biologics Co., Ltd.
- Current Assignee: KM Biologics Co., Ltd.
- Current Assignee Address: JP Kumamoto
- Agency: Pillsbury Winthrop Shaw Pittman LLP
- Priority: JPJP2017-165684 20170830
- International Application: PCT/JP2018/032020 WO 20180829
- International Announcement: WO2019/044927 WO 20190307
- Main IPC: C07K14/005
- IPC: C07K14/005 ; A61P31/22 ; A61K39/245
Abstract:
A modified protein of a herpes simplex virus (HSV) envelope glycoprotein B (gB), in which at least one non-neutralizing antibody-inducing epitope (non-neutralizing epitope) present in domain IV and domain I of wild-type HSV gB is inactivated (de-epitoped).
Public/Granted literature
- US20200299334A1 MODIFIED HSV GB PROTEIN AND HSV VACCINE INCLUDING SAME Public/Granted day:2020-09-24
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