Methods for enhancing the efficiency of gene editing

Invention Grant

US11421218B2 Methods for enhancing the efficiency of gene editing 有权

Patent Title: Methods for enhancing the efficiency of gene editing
Application No.: US16086559

Application Date: 2017-03-23
Publication No.: US11421218B2

Publication Date: 2022-08-23
Inventor: Alan D'Andrea , Markus Grompe
Applicant: Dana-Farber Cancer Institute, Inc. , Oregon Health & Science University
Applicant Address: US MA Boston; US OR Portland
Assignee: Dana-Farber Cancer Institute, Inc.,Oregon Health & Science University
Current Assignee: Dana-Farber Cancer Institute, Inc.,Oregon Health & Science University
Current Assignee Address: US MA Boston; US OR Portland
Agency: Fish & Richardson P.C.
International Application: PCT/US2017/023828 WO 20170323
International Announcement: WO2017/165655 WO 20170928
Main IPC: C12N15/10
IPC: C12N15/10

Abstract:

The present invention provides methods of increasing the efficiency of genome editing.

Public/Granted literature

Information query

Espacenet

IPC分类:

C	化学；冶金
C12	生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程
C12N	微生物或酶；其组合物；繁殖、保藏或维持微生物；变异或遗传工程；培养基（微生物学的试验介质入C12Q1/00）。
C12N15/00	突变或遗传工程；遗传工程涉及的DNA或RNA，载体（如质粒）或其分离、制备或纯化；所使用的宿主（突变体或遗传工程制备的微生物本身入C12N1/00、C12N5/00、C12N7/00；新的植物入A01H；用组织培养技术再生植物入A01H4/00；新的动物入A01K67/00；含有插入活体细胞的遗传物质以治疗遗传疾病的药剂的应用，基因疗法入A61K48/00，一般肽入C07K）
C12N15/09	.DNA重组技术
C12N15/10	..分离、制备或纯化DNA或RNA的方法（DNA或RNA的化学制备入C07H21/00；自微生物中或用酶制备非结构多核苷酸入C12P19/34）