Invention Grant
- Patent Title: Aptamers for targeting coagulation factor XIII and uses thereof
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Application No.: US16699742Application Date: 2019-12-02
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Publication No.: US11421234B2Publication Date: 2022-08-23
- Inventor: Yunn-Hwa Ma , Ching-Ping Tseng , Kai-Wen Cheng
- Applicant: Chang Gung University
- Applicant Address: TW Taoyuan
- Assignee: Chang Gung University
- Current Assignee: Chang Gung University
- Current Assignee Address: TW Taoyuan
- Main IPC: C12N15/115
- IPC: C12N15/115 ; A61K48/00 ; A61K47/54 ; A61K45/06
Abstract:
Provided herein is an aptamer specific to coagulation factor XIII (FXIII) and its uses thereof. Accordingly, the present aptamer is useful as a bio-tool to label thrombi, and/or as a targeting molecule to deliver drugs to thrombotic area. Therefore, the present disclosure also pertains to methods for treating diseases associated with FXIII, such as thrombosis.
Public/Granted literature
- US20210163945A1 APTAMERS FOR TARGETING COAGULATION FACTOR XIII AND USES THEREOF Public/Granted day:2021-06-03
Information query
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