Invention Grant
- Patent Title: Methods for identification of driver mutations in a patient tumor by mutation processing based reconstruction of tumor developmental history
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Application No.: US16484772Application Date: 2018-02-23
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Publication No.: US11421281B2Publication Date: 2022-08-23
- Inventor: Donghai Dai
- Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
- Applicant Address: US IA Iowa City
- Assignee: UNIVERSITY OF IOWA RESEARCH FOUNDATION
- Current Assignee: UNIVERSITY OF IOWA RESEARCH FOUNDATION
- Current Assignee Address: US IA Iowa City
- Agency: Viksnins Harris Padys Malen LLP
- International Application: PCT/US2018/019436 WO 20180223
- International Announcement: WO2018/156904 WO 20180830
- Main IPC: C12Q1/6806
- IPC: C12Q1/6806 ; C12Q1/6886
Abstract:
In certain embodiments, the present invention provides a method to identify driver mutations in a tumor and its cancer cell subpopulations. The method of the present invention is used to design treatment strategies for cancer patients.
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