Ladders, ladder components and related methods are provided. In some embodiments, adjustable stepladders are provided which include locking mechanisms that enable height adjustment of the ladder through application of a force towards the rails of the ladder. The locking mechanism may include a base or bracket, a handle or lever pivotally coupled with the bracket, an engagement pin coupled with the lever, a biasing member to bias the handle towards a first position relative to the bracket, and a detent mechanism for retaining the lever in at least a second position relative to the bracket.