The disclosure relates to the field of digital pathology imaging technologies, in particular, to a digital pathology scanner for large-area microscopic imaging. The digital pathology scanner for large-area microscopic imaging includes a plurality of microscopic objectives and a plurality of digital image sensors; the microscopic objectives and the digital image sensors are equal in quantity and are fixed relatively in a one-to-one correspondence manner. The digital image sensors are sequentially distributed so as to form a sensor array. The sensor array enables images formed by the digital image sensors to be sequentially distributed without intervals in a second direction when moving in a first direction, wherein the first direction is perpendicular to the second direction.