The present supply chain management system has an e-commerce subsystem having a product inventory database comprising product SKU and pricing data and an e-commerce frontend interfacing the product inventory database for receiving retailer e-commerce orders. The system also has an order management subsystem having an aggregation controller for aggregating the retailer e-commerce orders into supply orders, an aggregation optimizer for optimizing the supply orders; and an order dispatch controller for dispatching the supply orders to suppliers. The system also has an electronic warehouse infrastructure having a pick grid controller having product tracking electronic scanning devices, the pick grid controller configured for generating pick grid instructions for pick-to-zero product placement from supplier pallets received for the supply orders to order pallets configured according to the retailer e-commerce orders.