Invention Grant
- Patent Title: Treatment for Wolfram syndrome and other endoplasmic reticulum stress disorders
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Application No.: US16491826Application Date: 2018-03-06
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Publication No.: US11426415B2Publication Date: 2022-08-30
- Inventor: Fumihiko Urano , Jana Mahadevan , Amy Clark , Ajit Jadhav , David Maloney , Brandon Harvey , Shyh-ming Yang , Mark Henderson
- Applicant: Washington University , The United States of America, As Represented by the Secretary, Department of Health and Human Services, Office of Technology Transfer, National Institutes of Health
- Applicant Address: US MO St. Louis; US MD Bethesda
- Assignee: Washington University,The United States of America, As Represented by the Secretary, Department of Health and Human Services, Office of Technology Transfer, National Institutes of Health
- Current Assignee: Washington University,The United States of America, As Represented by the Secretary, Department of Health and Human Services, Office of Technology Transfer, National Institutes of Health
- Current Assignee Address: US MO St. Louis; US MD Bethesda
- Agency: Stinson LLP
- International Application: PCT/US2018/021167 WO 20180306
- International Announcement: WO2018/165171 WO 20180913
- Main IPC: A61K31/554
- IPC: A61K31/554 ; A61K9/00 ; A61K31/155 ; A61K31/4178 ; A61K31/4985 ; A61K45/06 ; C07K14/605
Abstract:
The present invention generally relates to compositions and methods for treating or preventing an endoplasmic reticulum stress disorder in subjects, including compositions and methods for treating or preventing Wolfram syndrome. The present invention also relates to methods for treating symptoms of neurodegenerative diseases.
Public/Granted literature
- US20210128580A1 TREATMENT FOR WOLFRAM SYNDROME AND OTHER ENDOPLASMIC RETICULUM STRESS DISORDERS Public/Granted day:2021-05-06
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