Invention Grant
- Patent Title: Complex of gadolinium and a chelating ligand derived of a diastereoisomerically enriched PCTA and synthesis method
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Application No.: US17397022Application Date: 2021-08-09
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Publication No.: US11426470B2Publication Date: 2022-08-30
- Inventor: Soizic Le Greneur , Alain Chénedé , Martine Cerf , Stéphane Decron , Bruno François
- Applicant: GUERBET
- Applicant Address: FR Villepinte
- Assignee: GUERBET
- Current Assignee: GUERBET
- Current Assignee Address: FR Villepinte
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- Priority: FR1900433 20190117
- Main IPC: A61B5/055
- IPC: A61B5/055 ; A61K49/10 ; C07D471/08 ; C07F5/00
Abstract:
The present invention relates to a complex of formula (II) constituted of at least 80% of a diastereoisomeric excess comprising a mixture of isomers II-RRR and II-SSS of formulae: The present invention also relates to a process for preparing said complex of formula (II), and also to two synthetic intermediates.
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