A method and device for optimizing tests of systems, in particular of an aircraft, including a first display module displaying a list of tests that can be executed by systems, a selection module allowing an operator to select a set of tests to be executed and communicate it to an optimization module which determines a sequence of tests representing an optimized execution of the set of tests to be executed, the sequence of tests being displayed by a second display module for an operator, a decision module generating either a first signal if the operator validates the sequence of tests, or a second signal if the operator cancels the sequence of tests, and a control module which, if the first signal is generated, commands the execution of the sequence of tests by each of the systems, and generates results of the execution thereof.