Invention Grant
- Patent Title: Aryl cyclopropyl-amino-isoquinolinyl amide compounds
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Application No.: US16570849Application Date: 2019-09-13
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Publication No.: US11427563B2Publication Date: 2022-08-30
- Inventor: Mitchell A. deLong , Jill M. Sturdivant , Cynthia L. Lichorowic , Andriy Kornilov
- Applicant: Aerie Pharmaceuticals, Inc.
- Applicant Address: US NJ Bedminster
- Assignee: Aerie Pharmaceuticals, Inc.
- Current Assignee: Aerie Pharmaceuticals, Inc.
- Current Assignee Address: US NJ Bedminster
- Agency: K&L Gates LLP
- Agent Louis C. Cullman; Benjamin D. Heuberger
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D417/12 ; C07D401/12 ; A61P27/06 ; C07D413/12 ; C07D405/12 ; C07D417/14
Abstract:
Provided herein are amino isoquinolinyl amide and sulfonamide compounds that affect the function of kinases and other proteins in a cell and that are useful as therapeutic agents. In particular, these compounds are useful in the treatment of eye diseases such as glaucoma and retinal diseases, as anti-inflammatory agents, for the treatment of cardiovascular diseases, and for diseases characterized by abnormal growth, such as cancers.
Information query
