- Patent Title: Aryl receptor modulators and methods of making and using the same
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Application No.: US15321967Application Date: 2015-06-26
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Publication No.: US11427600B2Publication Date: 2022-08-30
- Inventor: Francesca Viti , Salvatore Bellinvia , Salvatore Demartis
- Applicant: Nogra Pharma Limited
- Applicant Address: IE Dublin
- Assignee: Nogra Pharma Limited
- Current Assignee: Nogra Pharma Limited
- Current Assignee Address: IE Dublin
- Agency: Goodwin Procter LLP
- International Application: PCT/EP2015/064613 WO 20150626
- International Announcement: WO2015/197861 WO 20151230
- Main IPC: C07D495/14
- IPC: C07D495/14 ; C07D471/04 ; C07D487/04 ; C07D495/04 ; C07C233/29 ; C07C233/73 ; C07C235/38 ; C07C235/46 ; C07D209/08 ; C07D209/14 ; C07D209/86 ; C07D209/94 ; C07D213/75 ; C07D235/30 ; C07D277/64 ; C07D277/82 ; C07D333/36
Abstract:
The present invention is generally directed towards compounds capable of binding the aryl hydrocarbon receptor and modulating its activity, methods of treating inflammatory conditions such as Crohn's disease using such compounds, and pharmaceutical compositions comprising such compounds. Also provided are methods of increasing levels of IL-22 in a subject and/or decreasing levels of IFN-γ in a subject.
Public/Granted literature
- US20170158707A1 ARYL RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME Public/Granted day:2017-06-08
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