Invention Grant
![Crystalline forms of 5-chloro-N4-[-2-(dimethylphosphoryl) phenyl]-N2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl) piperidin-1-yl] phenyl} pyrimidine-2,4-diamine](/docs/US/2022-08-30/US11427605B2/abs.jpg.600x600.jpg)
- Patent Title: Crystalline forms of 5-chloro-N4-[-2-(dimethylphosphoryl) phenyl]-N2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl) piperidin-1-yl] phenyl} pyrimidine-2,4-diamine
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Application No.: US17124407Application Date: 2020-12-16
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Publication No.: US11427605B2Publication Date: 2022-08-30
- Inventor: Leonard W. Rozamus , Pradeep Sharma
- Applicant: ARIAD Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: ARIAD Pharmaceuticals, Inc.
- Current Assignee: ARIAD Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Honigman LLP
- Agent Andrew S. Chipouras; Jonathan P. O'Brien
- Main IPC: C07F9/6558
- IPC: C07F9/6558 ; C07D239/48
![Crystalline forms of 5-chloro-N4-[-2-(dimethylphosphoryl) phenyl]-N2-{2-methoxy-4-[4-(4-methylpiperazin-1-yl) piperidin-1-yl] phenyl} pyrimidine-2,4-diamine](/abs-image/US/2022/08/30/US11427605B2/abs.jpg.150x150.jpg)
Abstract:
Novel crystalline forms of brigatinib, pharmaceutical compositions comprising the same, and methods of their preparation and use of the same are disclosed herein.
Public/Granted literature
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