Invention Grant
- Patent Title: Polynucleotides encoding humanized antibodies against CEACAM1
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Application No.: US16700490Application Date: 2019-12-02
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Publication No.: US11427647B2Publication Date: 2022-08-30
- Inventor: Tehila Ben-Moshe , Yair Sapir , Ilana Mandel , Gal Markel , Jacob Schachter , Rona Ortenberg , Francis Joseph Carr , Robert George E. Holgate , Timothy David Jones
- Applicant: Famewave Ltd.
- Applicant Address: IL Rehovot
- Assignee: Famewave Ltd.
- Current Assignee: Famewave Ltd.
- Current Assignee Address: IL Rehovot
- Agency: Rothwell, Figg, Ernst & Manbeck, P.C.
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C07K16/30 ; G01N33/574 ; C12N15/62 ; A61K39/395 ; C07K16/28 ; A61K39/00 ; A61K35/17 ; A61K45/06
Abstract:
Humanized antibodies, capable of specific binding to human CEACAM1 molecules containing human-to-murine back-mutations in non-CDR variable regions, and their encoding polynucleotide sequences are provided. Pharmaceutical compositions comprising these antibodies as well as methods of their use in treating and diagnosing cancer and other conditions are also provided.
Public/Granted literature
- US20200216557A1 HUMANIZED ANTIBODIES AGAINST CEACAM1 Public/Granted day:2020-07-09
Information query
IPC分类:
