Invention Grant
- Patent Title: Chlorinated derivative of hyaluronic acid, method of preparation thereof, a composition containing the derivative, and use thereof
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Application No.: US17270693Application Date: 2019-08-17
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Publication No.: US11427652B2Publication Date: 2022-08-30
- Inventor: Radovan Buffa , Ivana Basarabova , Martina Hermannova , Katerina Knotkova , Jaromir Kulhanek , Josef Chmelar , Tomá{hacek over (s)} Pitucha , Drahomira Chladkova , Helena Krejci , Hana Vagnerova , Martin Sojka , Lubos Sobotka , Vladimir Velebny
- Applicant: CONTIPRO A.S.
- Applicant Address: CZ Dolni Dobrouc
- Assignee: CONTIPRO A.S.
- Current Assignee: CONTIPRO A.S.
- Current Assignee Address: CZ Dolni Dobrouc
- Agency: Lorenz & Kopf LLP
- Priority: CZCZ2018-426 20180823
- International Application: PCT/CZ2019/050034 WO 20190817
- International Announcement: WO2020/038500 WO 20200227
- Main IPC: C08B37/08
- IPC: C08B37/08 ; A61P31/04 ; A61K31/728 ; A61L15/28 ; A61L27/20
Abstract:
A chlorinated derivative of hyaluronic acid or of a modified hyaluronic acid (chloramide) is provided. The chloramide has an amidic group (—NH—CO—). The hydrogen of the amidic group is substituted by a chlorine atom, according to the structural formula —NCl—CO—. The substitution degree of the hyaluronic acid or of the modified hyaluronic acid by chlorine is in an amount of from 50 to 100 %.
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