Invention Grant
- Patent Title: Fungal genome modification systems and methods of use
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Application No.: US15536836Application Date: 2015-12-15
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Publication No.: US11427829B2Publication Date: 2022-08-30
- Inventor: Benjamin S. Bower , Jimmy Chan , Jing Ge , Xiaogang Gu , Susan Mampusti Madrid , Danfeng Song , Mingmin Song , Michael Ward
- Applicant: Danisco US Inc.
- Applicant Address: US CA Palo Alto
- Assignee: Danisco US Inc.
- Current Assignee: Danisco US Inc.
- Current Assignee Address: US CA Palo Alto
- Priority: WOPCT/CN2014/093914 20141216,WOPCT/CN2014/093916 20141216,WOPCT/CN2014/093918 20141216
- International Application: PCT/US2015/065693 WO 20151215
- International Announcement: WO2016/100272 WO 20160623
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C12N15/80 ; C12N9/22 ; C12N15/11

Abstract:
Compositions and methods are provided for genome modification at a target site in the genome of a filamentous fungal cell. The methods and compositions are drawn to a guide polynucleotide/Cas endonuclease system for modifying or altering the target site. Aspects in which the filamentous fungal cell being modified has a defective non-homologous end joining pathway are also provided.
Public/Granted literature
- US20180002710A1 FUNGAL GENOME MODIFICATION SYSTEMS AND METHODS OF USE Public/Granted day:2018-01-04
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