The present disclosure discloses an air conditioning system, an operating method and an operating device of the air conditioning system. The air conditioning system includes multiple outdoor units and multiple indoor units. The multiple indoor units include a first indoor unit configured to have wired communication and a second indoor unit configured to have wireless communication. The multiple outdoor units includes a first model outdoor unit connected with the first indoor unit configured to have wired communication, a second model outdoor unit corresponding to the second indoor unit, and a main outdoor unit configured to receive communication information from the first indoor unit and/or the second indoor unit, determine a target outdoor unit for communication on the basis of the communication information, and send the communication information to the target outdoor unit for communication.