An integrated circuit (IC), a display device and an anti-interference method thereof are provided. The IC includes an input pad, a source driving circuit and an anti-interference circuit. The input pad receives an input signal comprising image data from the external. The source driving circuit is coupled to the input pad to receive the input signal. The anti-interference circuit is coupled to the input pad to provide a variable capacitance. The anti-interference circuit adjusts the variable capacitance from a normal capacitance value to at least one anti-interference capacitance value when an interference event occurs to the input signal. The anti-interference circuit maintains the variable capacitance at the normal capacitance value when the interference event does not occur.