The present disclosure provides a chassis and an electronic device applying the chassis. The chassis includes: a chassis body; the chassis body is a 2U chassis body or a 4U chassis body; a hard disk module, installed in a front end area of the chassis body; a power supply module, installed at one side of a rear end area of the chassis body; a controller module, installed in a remaining rear end area of the chassis body except the power supply module, parallel with the power supply module, and including a plurality of pluggable functional modules; a middle board, connected with the power supply module, the hard disk module, and the control module, respectively, to realize the electrical connection between the power supply module, the hard disk module, and the control module. The present disclosure can improve the versatility of the chassis modules.