Invention Grant
- Patent Title: Methods of use and pharmaceutical combinations comprising histone deacetylase inhibitors and JAK1/2 inhibitors
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Application No.: US16768439Application Date: 2018-11-30
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Publication No.: US11433069B2Publication Date: 2022-09-06
- Inventor: Samantha Pozzi , Maria Cosenza , Monica Civallero
- Applicant: University of Modena and Reggio Emilia
- Applicant Address: IT Modena
- Assignee: University of Modena and Reggio Emilia
- Current Assignee: University of Modena and Reggio Emilia
- Current Assignee Address: IT Modena
- Agency: Lathrop GPM LLP
- Agent Brian Trinque
- International Application: PCT/IB2018/059540 WO 20181130
- International Announcement: WO2019/106633 WO 20190606
- Main IPC: A61K31/505
- IPC: A61K31/505 ; A61P35/02 ; A61K31/5377
Abstract:
The disclosure relates to pharmaceutical combinations comprising an HDAC6 selective inhibitor and a JAK1/2 inhibitor for the treatment of a cancer, such as a hematological cancer, in a subject in need thereof. Also provided herein are methods for treating a cancer in a subject in need thereof, comprising administering to the subject an effective amount of an HDAC6 selective inhibitor and a JAK1/2 inhibitor.
Information query
