Invention Grant
- Patent Title: Compositions and methods for treatment of cancers harboring an H3K27M mutation
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Application No.: US16629604Application Date: 2018-07-12
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Publication No.: US11433098B2Publication Date: 2022-09-06
- Inventor: Michelle Monje-Deisseroth , Robbie Majzner , Crystal Mackall , Christopher Mount
- Applicant: The Board of Trustees of the Leland Stanford Junior University
- Applicant Address: US CA Stanford
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Stanford
- Agency: Casimir Jones, S.C.
- Agent Kelly A. Barton
- International Application: PCT/US2018/041839 WO 20180712
- International Announcement: WO2019/014456 WO 20190117
- Main IPC: A61K35/17
- IPC: A61K35/17 ; A61P35/00 ; A61K45/06 ; C07K16/30
Abstract:
The invention relates to immunotherapeutic treatment of cancer. In particular, the invention relates to methods of treating cancer carrying a histone H3K27M (H3K27M) mutation (e.g., diffuse midline glioma with H3K27M mutation) using immunotherapeutic compositions comprising immune cells engineered to express GD2-specific chimeric antigen receptors.
Public/Granted literature
- US20210137979A1 COMPOSITIONS AND METHODS FOR TREATMENT OF CANCERS HARBORING AN H3K27M MUTATION Public/Granted day:2021-05-13
Information query
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