Invention Grant
- Patent Title: Composition for treating fine dust-caused skin cell damage or for inhibiting antimicrobial peptide, comprising Hibiscus syriacus extract
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Application No.: US16651880Application Date: 2018-08-20
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Publication No.: US11433110B2Publication Date: 2022-09-06
- Inventor: Hyoung-June Kim , Tae Ryong Lee
- Applicant: AMOREPACIFIC CORPORATION
- Applicant Address: KR Seoul
- Assignee: AMOREPACIFIC CORPORATION
- Current Assignee: AMOREPACIFIC CORPORATION
- Current Assignee Address: KR Seoul
- Agency: Sughrue Mion, PLLC
- Priority: KR10-2017-0127665 20170929,KR10-2017-0127667 20170929
- International Application: PCT/KR2018/009516 WO 20180820
- International Announcement: WO2019/066252 WO 20190404
- Main IPC: A61K36/00
- IPC: A61K36/00 ; A61K36/185 ; A23L33/105 ; A61K8/9789 ; A61Q19/00

Abstract:
Disclosed is a composition including a Hibiscus syriacus extract as an effective ingredient for treating fine dust-caused skin damage, wherein the expression of at least one selected from the group consisting of IL-36G (NM_019618), PTGS2 (NM_000963), XDH (NM_000379) and S100A7 (NM_002963), which are all genes having the expression levels affected by fine dust in skin cells, is regulated to a normal level and for inhibiting an antibacterial peptide, wherein the expression of the antibacterial peptide S100A7 (NM_002963) is regulated to a normal level. By using the composition for treating fine dust-caused skin damage and the composition for inhibiting an antibacterial peptide, gene expression changed by fine dust can return to a normal level to treat skin cell damage and the increased expression of the antibacterial peptide due to various causes can return to normal level.
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