Invention Grant
- Patent Title: Long-acting VEGF inhibitors for intraocular neovascularization
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Application No.: US17522318Application Date: 2021-11-09
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Publication No.: US11433118B2Publication Date: 2022-09-06
- Inventor: Napoleone Ferrara
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Eversheds Sutherland (US) LLP
- Main IPC: A61K38/16
- IPC: A61K38/16 ; A61K38/18 ; C07K14/71 ; C07K16/00 ; C12N9/12 ; A61K39/395 ; A61K38/17 ; A61P27/02
Abstract:
Compositions and methods for treating a VEGF-related ophthalmic disorder in a subject in need comprising, administering intravitreally to the subject a therapeutically effective amount of an anti-VEGF agent, comprising a VEGF binding portion operatively linked to a Fc-IgG, wherein the VEGF binding portion comprises at least one VEGF binding domain that is an IgG-like domain 2 of VEGFR-1.
Public/Granted literature
- US20220088128A1 LONG-ACTING VEGF INHIBITORS FOR INTRAOCULAR NEOVASCULARIZATION Public/Granted day:2022-03-24
Information query
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