Invention Grant
- Patent Title: Adoptive cell therapy using spherical nucleic acids (SNAs)
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Application No.: US16611502Application Date: 2018-05-11
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Publication No.: US11433131B2Publication Date: 2022-09-06
- Inventor: Chad A. Mirkin , Andrew Lee , Bin Zhang , Donye Dominguez
- Applicant: Northwestern University
- Applicant Address: US IL Evanston
- Assignee: Northwestern University
- Current Assignee: Northwestern University
- Current Assignee Address: US IL Evanston
- Agency: Marshall, Gerstein & Borun LLP
- International Application: PCT/US2018/032372 WO 20180511
- International Announcement: WO2018/209270 WO 20181115
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A61K39/39 ; A61P35/00 ; A61K39/00 ; C12N15/113
Abstract:
The disclosure is related to compositions comprising a cell and a spherical nucleic acid (SNA) comprising a nanoparticle, an oligonucleotide on the surface of the nanoparticle, and an antigen; and to methods for production of such compositions and their applications, including but not limited to adoptive cell therapy.
Information query
