Invention Grant
- Patent Title: Polyacetal polymers, conjugates, particles and uses thereof
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Application No.: US16063353Application Date: 2016-12-16
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Publication No.: US11433136B2Publication Date: 2022-09-06
- Inventor: Peter Blume-Jensen , Donald E. Chickering, III , Paul W. Kopesky , Lawrence A. Reiter , Alan Crane , Robert S. Langer , Rong Tong , Rakesh K. Jain , Vikash Pal Singh Chauhan , Joao Incio , Dai Fukumura
- Applicant: THE GENERAL HOSPITAL CORPORATION , MASSACHUSETTS INSTITUTE OF TECHNOLOGY , XTUIT PHARMACEUTICALS, INC.
- Applicant Address: US MA Boston; US MA Cambridge; US MA Waltham
- Assignee: THE GENERAL HOSPITAL CORPORATION,MASSACHUSETTS INSTITUTE OF TECHNOLOGY,XTUIT PHARMACEUTICALS, INC.
- Current Assignee: THE GENERAL HOSPITAL CORPORATION,MASSACHUSETTS INSTITUTE OF TECHNOLOGY,XTUIT PHARMACEUTICALS, INC.
- Current Assignee Address: US MA Boston; US MA Cambridge; US MA Waltham
- Agency: Nixon Peabody LLP
- Agent David S. Resnick; Ravinderjit Braich
- International Application: PCT/US2016/067149 WO 20161216
- International Announcement: WO2017/106630 WO 20170622
- Main IPC: A61K47/60
- IPC: A61K47/60 ; A61K9/14 ; A61K31/41 ; A61K31/4184 ; A61K31/4545 ; A61P35/00 ; C08G65/48
Abstract:
Provided herein are polymers, pH-sensitive polymers and/or linkers; conjugates comprising said polymers and/or linkers, optionally, coupled to one or more agents and/or targeting moieties; and particles (e.g., nanoparticles comprising the aforesaid polymers, linkers and/or conjugates), which can be used to enhance the delivery and/or efficacy of one or more agents in a subject.
Public/Granted literature
- US20180360978A1 POLYACETAL POLYMERS, CONJUGATES, PARTICLES AND USES THEREOF Public/Granted day:2018-12-20
Information query
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