A fastening system for fastening loads on vehicles includes a load slide arranged on and movable on a load rail along an extension direction. The load slide includes a fastening device for fastening a securing element and is lockable at different travel positions on the load rail. On the outside of the load rail a plurality of locking recesses are formed along the extension direction. The load slide includes a rotatably mounted cam, which is rigidly connected to an actuating element and which can be rotated with the actuating element between a locked position and an unlocked position. In the locked position, the cam can engage with one of the locking recesses and thus lock the travel position of the load slide. In the unlocked position, the cam is disengaged with respect to the locking recesses and the load slide can thus be moved on the load rail.