Invention Grant
- Patent Title: Compounds and methods for the treatment of neurodegenerative diseases
-
Application No.: US17208875Application Date: 2021-03-22
-
Publication No.: US11434198B2Publication Date: 2022-09-06
- Inventor: Francis Xavier Tavares , Michael Peter Vitek
- Applicant: Resilio Therapeutics, LLC
- Applicant Address: US NC Durham
- Assignee: Resilio Therapeutics, LLC
- Current Assignee: Resilio Therapeutics, LLC
- Current Assignee Address: US NC Durham
- Agency: Schwegman Lundberg & Woessner, P.A.
- Main IPC: C07C229/26
- IPC: C07C229/26 ; C07D317/38 ; A61P25/28 ; A61P25/00 ; A61P35/00 ; A61K45/06
Abstract:
Novel compounds of formula (II) are disclosed. Compounds of formula (II) comprise ornithine derivatives or compounds that can metabolize under physiological conditions to ornithine. The pH and plasma stability of compounds of formula (II) is also described. Also disclosed are methods for the treatment of neurodegenerative diseases such as Alzheimer's Disease using compounds of formula (II).
Public/Granted literature
- US20210206713A1 COMPOUNDS AND METHODS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES Public/Granted day:2021-07-08
Information query
