Invention Grant
- Patent Title: Method for synthesis of lobaric acid and analog thereof
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Application No.: US16958794Application Date: 2018-07-23
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Publication No.: US11434217B2Publication Date: 2022-09-06
- Inventor: Joung Han Yim , Il-Chan Kim , Se Jong Han , Ui Joung Youn , Hong Kum Lee , Jun Hyuck Lee , Tai Kyoung Kim , Kwon Joo Yeo
- Applicant: KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY
- Applicant Address: KR Busan
- Assignee: KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY
- Current Assignee: KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY
- Current Assignee Address: KR Busan
- Agency: Hultquist, PLLC
- Agent Steven J. Hultquist
- Priority: KR10-2017-0183674 20171229
- International Application: PCT/KR2018/008254 WO 20180723
- International Announcement: WO2019/132148 WO 20190704
- Main IPC: C07D307/88
- IPC: C07D307/88

Abstract:
The present invention can synthesize lobaric acid and four analogues thereof, which are five phenolic lichen metabolites isolated from an extract of the Antarctic lichen Stereocaulon alpinum and selectively inhibit PTP1B, by a simple, economic and efficient chemical synthesis method.
Public/Granted literature
- US20210246112A1 METHOD FOR SYNTHESIS OF LOBARIC ACID AND ANALOG THEREOF Public/Granted day:2021-08-12
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