Invention Grant
- Patent Title: Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
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Application No.: US17058403Application Date: 2019-05-29
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Publication No.: US11434244B2Publication Date: 2022-09-06
- Inventor: David D. Ginty , Lauren L. Orefice , Jinbo Lee
- Applicant: President and Fellows of Harvard College
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2019/034390 WO 20190529
- International Announcement: WO2019/232046 WO 20191205
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/437 ; C07D487/04 ; A61P25/04
Abstract:
The present invention features novel peripherally-restricted non-benzodiazipene analogs with reduced blood brain barrier permeability and methods of use thereof for reducing tactile dysfunction, social impairment, and anxiety in a subject diagnosed with Autism Spectrum Disorder, Rett syndrome, Phelan McDermid syndrome, or Fragile X syndrome, or for treating touch over-reactivity, pain, or mechanical allodynia.
Public/Granted literature
- US20210206771A1 COMPOSITIONS AND METHODS FOR REDUCING TACTILE DYSFUNCTION, ANXIETY, AND SOCIAL IMPAIRMENT Public/Granted day:2021-07-08
Information query
