Invention Grant
- Patent Title: Stabilized polypeptides and uses thereof
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Application No.: US16955557Application Date: 2019-01-04
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Publication No.: US11434263B2Publication Date: 2022-09-06
- Inventor: Martin Karplus , Victor G Ovchinnkov
- Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Applicant Address: US MA Cambridge
- Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Current Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Current Assignee Address: US MA Cambridge
- Agency: Hogan Lovells US LLP
- International Application: PCT/US2019/012291 WO 20190104
- International Announcement: WO2019/136209 WO 20190711
- Main IPC: A61K38/10
- IPC: A61K38/10 ; C07K7/08 ; C07K14/195 ; A61K38/00
Abstract:
The present invention features polypeptides which inhibit dimerization of small multidrug resistance transporters including a stabilized α-helix, and the use of such polypeptides in the treatment of bacterial infections.
Public/Granted literature
- US20200317736A1 STABILIZED POLYPEPTIDES AND USES THEREOF Public/Granted day:2020-10-08
Information query
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