Invention Grant
- Patent Title: Method for high-throughput screening of neutralizing antibodies, neutralizing antibodies produced therefrom, and uses thereof
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Application No.: US16757460Application Date: 2018-10-19
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Publication No.: US11434277B2Publication Date: 2022-09-06
- Inventor: An-Suei Yang , Ing-Chien Chen , Yi-Kai Chiu , Chung-Ming Yu , Cheng-Chung Lee , Chao-Ping Tung , Yueh-Liang Tsou , Yi-Jen Huang , Chia-Lung Lin , Hong-Sen Chen , Hwei-Jiung Wang
- Applicant: ACADEMIA SINICA
- Applicant Address: TW Taipei
- Assignee: ACADEMIA SINICA
- Current Assignee: ACADEMIA SINICA
- Current Assignee Address: TW Taipei
- Agency: Muncy, Geissler, Olds & Lowe, P.C.
- International Application: PCT/US2018/056627 WO 20181019
- International Announcement: WO2019/079671 WO 20190425
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/10
Abstract:
Disclosed herein are methods for high-throughput screening of a virus-specific neutralizing antibody. According to certain embodiments of the present disclosure, the virus is an influenza virus. Also disclosed herein are the antibodies selected by the high-throughput screening method, and the uses thereof in the prophylaxis and/or treatment of viral infection.
Public/Granted literature
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