Invention Grant
- Patent Title: Binding members to PD-L1
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Application No.: US16079210Application Date: 2017-02-24
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Publication No.: US11434294B2Publication Date: 2022-09-06
- Inventor: Abdijapar Shamshiev , Titus Kretzschmar , Miriam Droste , Douglas Phillips
- Applicant: CELL MEDICA INC.
- Applicant Address: US TX Houston
- Assignee: CELL MEDICA INC.
- Current Assignee: CELL MEDICA INC.
- Current Assignee Address: US TX Houston
- Agency: Arnold & Porter Kaye Scholer
- Priority: EP16020057 20160225
- International Application: PCT/EP2017/054367 WO 20170224
- International Announcement: WO2017/144681 WO 20170831
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; A61K35/17 ; A61K39/39 ; A61P35/00 ; A61K39/00 ; A61K45/06 ; C07K14/705 ; G01N33/68

Abstract:
The present invention relates to anti-PD-L1 binding members and in particular to monovalent, high potency PD-L1-binding antibody fragments being highly stable and soluble. Such binding members may be used in the treatment of cancer and inflammatory diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.
Public/Granted literature
- US20190055312A1 BINDING MEMBERS TO PD-L1 Public/Granted day:2019-02-21
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