The present invention relates to a plug and valve integrated cone valve pump with combined type movable and fixed three cylinders and two spiral centralizers, which is applied to suction working conditions in highly deviated well sections. It comprises three pump cylinders, which are combined type including two fixed cylinders and a dynamic cylinder, two centralizers, which are combined type including a dynamic spiral centralizer and fixed spiral centralizer, a fixed cone valve, a cylinder and plug integrated springing fixed cone valve, a fixed plunger and a movable guide rod cone valve to solve the problems such as stuck pump, eccentric wear between plunger and pump cylinder and valve leakage.