A computer implemented method for controlling read-out from a digital image sensor device, comprising a plurality of pixels, the method comprising the steps of setting a first read-out scheme, based on a first level of pixel binning and/or pixel skipping, reading, based on the first read-out scheme, from the digital image sensor device, a first image, determining an exposure value for the first image, based on the intensity value of each one of the first plurality of regions of the first image and comparing the exposure value with a predetermined maximum value. A second read-out scheme based on a second level of pixel binning and/or pixel skipping is set. The level of pixel binning and/or pixel skipping in the second read-out scheme is increased compared to the first read-out scheme, if the exposure value is higher than the predetermined maximum value. Based on the second read-out scheme, a subsequent second image is read. A system configured to perform the method is also described.