An open roof construction for a vehicle having at least one opening in the fixed roof, includes a stationary part for attachment to the roof. It carries at least two guide rails alongside the roof opening. At least one closure having a front and a rear side is supported by an operating mechanism guided on the guide rails. The closure is adjustable between a closed position, in which it closes the roof opening, and an open position in which it is at least partly moved out of the roof opening. The operating mechanism includes at least one first support member adjustably supporting the closure near its front side, and at least adjustable second support members adjustably supporting the closure a distance behind the front side. Each support member includes two separate drive sources to be able to adjust each support member independently in horizontal and vertical direction.