Invention Grant
- Patent Title: Process for the preparation of ribociclib and its salts
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Application No.: US16758773Application Date: 2018-10-26
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Publication No.: US11440912B2Publication Date: 2022-09-13
- Inventor: Sarbjot Singh Sokhi , Govind Singh , Saswata Lahiri , Maneesh Kumar Pandey , Raj Narayan Tiwari , Sonu Shukla , Sachin Musmade , Heena Dua , Walter Cabri
- Applicant: FRESENIUS KABI ONCOLOGY LIMITED
- Applicant Address: IN New Delhi
- Assignee: FRESENIUS KABI ONCOLOGY LIMITED
- Current Assignee: FRESENIUS KABI ONCOLOGY LIMITED
- Current Assignee Address: IN New Delhi
- Agency: Leydig, Volt & Mayer, Ltd.
- Priority: IN201711038128 20171027
- International Application: PCT/IB2018/058376 WO 20181026
- International Announcement: WO2019/082143 WO 20190502
- Main IPC: C07D487/04
- IPC: C07D487/04 ; B01J23/72 ; C07D401/04
Abstract:
The invention relates to a process for the preparation of ribociclib of formula V or its salts. The invention provides novel crystalline forms of ribociclib succinate and ribociclib trifluoroacetate. The present invention also relates to pharmaceutical compositions comprising a crystalline form of ribociclib succinate and at least a pharmaceutically acceptable carrier. It further relates to the use of such compositions in the treatment of cancer.
Public/Granted literature
- US20200277295A1 AN IMPROVED PROCESS FOR THE PREPARATION OF RIBOCICLIB AND ITS SALTS Public/Granted day:2020-09-03
Information query
