Invention Grant
- Patent Title: Surfactant compounds-clips for extraction and stabilization in solution of membrane proteins
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Application No.: US16492005Application Date: 2017-12-27
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Publication No.: US11440932B2Publication Date: 2022-09-13
- Inventor: Pierre Falson , Julien Dauvergne , Ahcène Boumendjel , Marine Peuchmaur , Kim Anh Nguyen , Sandrine Magnard
- Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , UNIVERSITE CLAUDE BERNARD LYON 1 , UNIVERSITE GRENOBLE ALPES
- Applicant Address: FR Paris; FR Villeurbanne; FR Saint-Martin d'Hères
- Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,UNIVERSITE CLAUDE BERNARD LYON 1,UNIVERSITE GRENOBLE ALPES
- Current Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,UNIVERSITE CLAUDE BERNARD LYON 1,UNIVERSITE GRENOBLE ALPES
- Current Assignee Address: FR Paris; FR Villeurbanne; FR Saint-Martin d'Hères
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: FR1751922 20170309
- International Application: PCT/FR2017/053857 WO 20171227
- International Announcement: WO2018/162806 WO 20180913
- Main IPC: C07H15/26
- IPC: C07H15/26 ; C07D249/04 ; C07K1/14
Abstract:
The present invention relates to a compound of formula (I): (I) as defined in the description. The present invention also relates to a method for extracting biological membrane-associated membrane proteins, comprising a step of bringing an aqueous solution of biological membrane-associated membrane proteins into contact with at least one compound of the invention. The present invention also relates to a method for stabilizing membrane proteins in solution in an aqueous solution, comprising a step (i) consisting in bringing an aqueous solution of a membrane protein in solution into contact with at least one compound of the invention.
Public/Granted literature
- US20210130385A1 SURFACTANT COMPOUNDS-CLIPS FOR EXTRACTION AND STABILIZATION IN SOLUTION OF MEMBRANE PROTEINS Public/Granted day:2021-05-06
Information query
