Invention Grant
- Patent Title: Anticancer peptides
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Application No.: US16634067Application Date: 2018-07-24
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Publication No.: US11440939B2Publication Date: 2022-09-13
- Inventor: Santiago Esteban Martín , Laura Nevola , Fernando Lecanda Cordero , Haritz Moreno Moreno
- Applicant: IDP DISCOVERY PHARMA, S.L.
- Applicant Address: ES Barcelona
- Assignee: IDP DISCOVERY PHARMA, S.L.
- Current Assignee: IDP DISCOVERY PHARMA, S.L.
- Current Assignee Address: ES Barcelona
- Agency: Seed IP Law Group LLP
- Priority: EP17382494 20170725
- International Application: PCT/EP2018/070073 WO 20180724
- International Announcement: WO2019/020649 WO 20190131
- Main IPC: C07K7/08
- IPC: C07K7/08 ; A61K47/62 ; A61P35/00 ; A61K38/00

Abstract:
The present invention provides a peptide of formula (I) or a pharmaceutical salt thereof wherein “m”, “n”, “p”, and “q” represent integers and are selected from 0 and 1; and “r” is comprised from 1 to 10; a linker biradical of formula (II), which is connecting an alpha carbon atom of an amino acid located at position “i” in the peptide sequence of formula (I) with an alpha carbon atom of an amino acid located at position “i+4” or “i+7” in the peptide sequence of formula (I); a C-terminal end corresponding to —C(O)R4; and a N-terminal end corresponding to —NHR5. The peptides of the invention show anticancer activity and an appropriate half-life and stability. Formula (I).
Public/Granted literature
- US20210230226A1 ANTICANCER PEPTIDES Public/Granted day:2021-07-29
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