Invention Grant
- Patent Title: Systems and methods to improve vaccine efficacy
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Application No.: US16474503Application Date: 2018-01-05
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Publication No.: US11440945B2Publication Date: 2022-09-13
- Inventor: Matthias Stephan
- Applicant: Fred Hutchinson Cancer Research Center
- Applicant Address: US WA Seattle
- Assignee: Fred Hutchinson Cancer Research Center
- Current Assignee: Fred Hutchinson Cancer Research Center
- Current Assignee Address: US WA Seattle
- Agency: Lee & Hayes PC
- Agent C. Rachal Winger
- International Application: PCT/US2018/012507 WO 20180105
- International Announcement: WO2018/129270 WO 20180712
- Main IPC: A61K39/39
- IPC: A61K39/39 ; A61P35/00 ; C07K14/725 ; A61K47/69 ; A61K47/68 ; A61K39/00 ; A61K9/00
Abstract:
Systems and methods to increase the efficacy of vaccines that require or are rendered more effective with T cell mediated immunity are described. The systems and methods utilize polynucleotides that genetically modify T cells to express a T cell receptor specific for an administered vaccine antigen.
Public/Granted literature
- US11566061B2 Systems and methods to improve vaccine efficacy Public/Granted day:2023-01-31
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