Invention Grant
- Patent Title: Target-specific CRISPR mutant
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Application No.: US16628199Application Date: 2018-07-06
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Publication No.: US11441135B2Publication Date: 2022-09-13
- Inventor: Young-Hoon Kim , Min Hee Jung , Joonsun Lee , Eunji Shin , Kang In Lee , Seokjoong Kim , Jeongjoon Lee
- Applicant: TOOLGEN INCORPORATED
- Applicant Address: KR Seoul
- Assignee: TOOLGEN INCORPORATED
- Current Assignee: TOOLGEN INCORPORATED
- Current Assignee Address: KR Seoul
- Agency: Harness, Dickey & Pierce, P.L.C.
- International Application: PCT/KR2018/007731 WO 20180706
- International Announcement: WO2019/009682 WO 20190110
- Main IPC: C12N9/22
- IPC: C12N9/22 ; C12N9/78 ; C12N15/86
Abstract:
The present invention relates to an artificially engineered CRISPR/Cas9 system. More particularly, the present invention relates to an artificially engineered CRISPR enzyme having enhanced target specificity and a use of an artificially engineered CRISPR/Cas9 system including the same enzyme in genome and/or epigenome manipulation or modification, genome targeting, genome editing, and in vitro diagnosis, etc.
Public/Granted literature
- US20200149022A1 TARGET-SPECIFIC CRISPR MUTANT Public/Granted day:2020-05-14
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