Invention Grant
- Patent Title: Methods and kits for depleting undesired nucleic acids
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Application No.: US15905952Application Date: 2018-02-27
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Publication No.: US11441175B2Publication Date: 2022-09-13
- Inventor: Suk Ho Eun , Adam Morris
- Applicant: BIOO Scientific Corporation
- Applicant Address: US TX Austin
- Assignee: BIOO Scientific Corporation
- Current Assignee: BIOO Scientific Corporation
- Current Assignee Address: US TX Austin
- Agency: Dinsmore & Shohl LLP
- Agent Julie K. Staple
- Main IPC: C12Q1/6848
- IPC: C12Q1/6848 ; C12Q1/6806 ; C12Q1/6832 ; C12Q1/6855 ; C12Q1/686 ; C12Q1/6874 ; C12Q1/6888 ; C12Q1/6811
Abstract:
Methods and kits for depleting amplicons that correspond to undesired RNA species present in a sample are provided. The disclosed methods and kits employ a blocker that anneals with at least a portion of the undesired RNA, resulting in a duplex that is not a suitable substrate for ligating an adapter to the end of the undesired RNA.
Public/Granted literature
- US20180258477A1 METHODS AND KITS FOR DEPLETING UNDESIRED NUCLEIC ACIDS Public/Granted day:2018-09-13
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