A guide for a piston of a high-pressure pump includes: an upper body and a lower body, a connection part integrally connecting the upper body and the lower body, and a seal molded by an insert injection between the upper body and the lower body while surrounding the connection part. A gap exists between the upper body and the lower body, and the piston and the seal are in close contact with a piston. Therefore, it is possible to prevent leakage of fuel even while securing motion performance of the piston.