Invention Grant
- Patent Title: Pyrimidinone-containing compound, preparation method thereof, pharmaceutical composition and application thereof
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Application No.: US16977775Application Date: 2019-03-04
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Publication No.: US11447470B2Publication Date: 2022-09-20
- Inventor: Yanping He , Hongbin Zhang , Yongtang Zheng , Yumeng Wu , Chengrun Tang , Ruomei Rui , Liumeng Yang , Jiangyuan Wang
- Applicant: YUNNAN UNIVERSITY , KUNMING INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES
- Applicant Address: CN Kunming; CN Kunming
- Assignee: YUNNAN UNIVERSITY,KUNMING INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES
- Current Assignee: YUNNAN UNIVERSITY,KUNMING INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES
- Current Assignee Address: CN Kunming; CN Kunming
- Agency: Pilloff Passino & Cosenza LLP
- Agent Sean A. Passino; Rachel K. Pilloff
- Priority: CN201810183285.5 20180306
- International Application: PCT/CN2019/076841 WO 20190304
- International Announcement: WO2019/170050 WO 20190912
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D403/14 ; C07D405/14 ; A61P31/18
Abstract:
Disclosed is a pyrimidinone-containing compound represented by formula I, a preparation method thereof, a pharmaceutical composition, and an application thereof. The pyrimidinone-containing compound of the present disclosure can be used as HIV-1 inhibitor and can be also used in the treatment of human immunodeficiency virus infection.
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