- Patent Title: Isoxazole N-linked carbamoyl cyclohexyl acids as LPA antagonists
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Application No.: US16954550Application Date: 2018-12-18
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Publication No.: US11447475B2Publication Date: 2022-09-20
- Inventor: Peter Tai Wah Cheng , Yan Shi , Robert F. Kaltenbach, III , Ying Wang , Hao Zhang
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agent Jing G. Sun
- International Application: PCT/US2018/066128 WO 20181218
- International Announcement: WO2019/126099 WO 20190627
- Main IPC: C07D413/04
- IPC: C07D413/04 ; C07D261/08
Abstract:
The present invention provides compounds of Formula (Ia) and (Ib): (Ia) or (Ib), or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.
Public/Granted literature
- US20200308157A1 ISOXAZOLE N-LINKED CARBAMOYL CYCLOHEXYL ACIDS AS LPA ANTAGONISTS Public/Granted day:2020-10-01
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