Invention Grant
- Patent Title: BACE1 inhibitors
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Application No.: US14783478Application Date: 2014-04-08
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Publication No.: US11447478B2Publication Date: 2022-09-20
- Inventor: Hans Hilpert , Roland Humm , Thorsten Muser , Christian Schnider , Roger Wermuth , Thomas Woltering
- Applicant: Hoffmann-La Roche Inc. , Siena Biotech S.p.A.
- Applicant Address: US NJ Nutley; IT Siena
- Assignee: Hoffmann-La Roche Inc.,Siena Biotech S.p.A.
- Current Assignee: Hoffmann-La Roche Inc.,Siena Biotech S.p.A.
- Current Assignee Address: US NJ Nutley; IT Siena
- Priority: EP13163430 20130411
- International Application: PCT/EP2014/056985 WO 20140408
- International Announcement: WO2014/166906 WO 20141016
- Main IPC: C07D413/14
- IPC: C07D413/14
Abstract:
The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
Public/Granted literature
- US20160052920A1 BACE1 INHIBITORS Public/Granted day:2016-02-25
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