Invention Grant
- Patent Title: Aromatic heterocyclic substituted olefin compound, preparation method for same, pharmaceutical composition of same, and applications thereof
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Application No.: US16964551Application Date: 2018-12-28
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Publication No.: US11447490B2Publication Date: 2022-09-20
- Inventor: Zusheng Xu , Yangtong Lou , Li Chen , Kun Zeng , Qingrui Sun , Xiaoli Lei
- Applicant: SHANGHAI YINGLI PHARMACEUTICAL CO., LTD
- Applicant Address: CN Shanghai
- Assignee: SHANGHAI YINGLI PHARMACEUTICAL CO., LTD
- Current Assignee: SHANGHAI YINGLI PHARMACEUTICAL CO., LTD
- Current Assignee Address: CN Shanghai
- Agency: Foley & Lardner LLP
- Priority: CN201810069892.9 20180124
- International Application: PCT/CN2018/124667 WO 20181228
- International Announcement: WO2019/144765 WO 20190801
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D401/06

Abstract:
Provided in the present application are an aromatic heterocyclic substituted olefin compound, a preparation method for same, a pharmaceutical composition of same, and applications thereof. The aromatic heterocyclic substituted olefin compound of the present invention is a novel ALK5 inhibitor and is for use in treating and/or preventing various ALK5-mediated diseases.
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