Invention Grant
- Patent Title: Anti-ALK2 antibody
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Application No.: US17511357Application Date: 2021-10-26
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Publication No.: US11447554B2Publication Date: 2022-09-20
- Inventor: Takenobu Katagiri , Kenji Osawa , Sho Tsukamoto , Shinnosuke Tsuji , Yoshirou Kawaguchi , Kensuke Nakamura
- Applicant: Saitama Medical University , Daiichi Sankyo Company, Limited
- Applicant Address: JP Saitama; JP Tokyo
- Assignee: Saitama Medical University,Daiichi Sankyo Company, Limited
- Current Assignee: Saitama Medical University,Daiichi Sankyo Company, Limited
- Current Assignee Address: JP Saitama; JP Tokyo
- Agency: Foley & Lardner LLP
- Priority: JP2015-017882 20150130
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00 ; C07K16/28 ; A61P7/06 ; A61P19/08 ; A61P35/00 ; A61K45/06
Abstract:
This application provides: an antibody which specifically binds to an ALK2 protein and has an activity of inhibiting BMP signal transduction mediated by ALK2; a method for producing the antibody; and a pharmaceutical composition comprising the antibody, for treating and/or preventing ectopic ossification and/or bone dysplasia, anemia, or diffuse intrinsic pontine glioma (DIPG).
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