Invention Grant
- Patent Title: Bispecific antigen binding molecules comprising anti-4-1BB clone 20H4.9
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Application No.: US16446486Application Date: 2019-06-19
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Publication No.: US11447558B2Publication Date: 2022-09-20
- Inventor: Claudia Ferrara Koller , Christina Claus , Christian Klein , Pablo Umaña , Wei Xu
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: US NJ Little Falls
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Little Falls
- Agent Robin A. Weatherhead
- Priority: EP17150150 20170103,EP17164224 20170331
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/40
Abstract:
The invention relates to new bispecific antigen binding molecules, comprising at least one antigen binding domain capable of specific binding to 4-1BB, at least one moiety capable of specific binding to a target cell antigen, and a Fc domain composed of a first and a second subunit capable of stable association, and to methods of producing these molecules and to methods of using the same.
Information query
