Invention Grant
- Patent Title: Evolution of tRNA synthetases
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Application No.: US16628456Application Date: 2018-07-03
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Publication No.: US11447809B2Publication Date: 2022-09-20
- Inventor: David R. Liu , David Irby Bryson, Jr.
- Applicant: President and Fellows of Harvard College
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- International Application: PCT/US2018/040692 WO 20180703
- International Announcement: WO2019/010164 WO 20190110
- Main IPC: C12P21/02
- IPC: C12P21/02 ; C12N9/00
Abstract:
The disclosure provides amino acid sequence variants of orthogonal aminoacyl-tRNA synthetases (AARSs) having increased activity and selectivity compared to previous AARSs, and methods of producing the same.
Public/Granted literature
- US20220154237A1 EVOLUTION OF TRNA SYNTHETASES Public/Granted day:2022-05-19
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